Neurapraxia is best described as which of the following?

• A. Complete axonal disruption with Wallerian degeneration
• B. Focal segmental demyelination with intact axon
• C. Global axonal injury with endoneurial disruption
• D. Nerve conduction blocked with no weakness

Answer: (B)

Neurapraxia is a mild nerve injury where the myelin sheath around the axon is transiently disrupted, causing a conduction block, but the axon itself and the surrounding connective tissue remain intact. Because the axon is preserved, there is no Wallerian degeneration, and recovery happens as the myelin is repaired, usually within days to weeks.

This fits best with focal segmental demyelination with an intact axon. The other descriptions describe more severe injuries: complete axonal disruption with Wallerian degeneration indicates axonotmesis; global axonal injury with endoneurial disruption points to neurotmesis; and a conduction block with no weakness would be inconsistent with the typical presentation of neurapraxia, which often includes some functional deficit due to the conduction block.